For a number of couples I know, one is self-employed or in a small business, while the other works for an organization that provides group insurance. Whether Big Co., the school system, some other aspect of government. Often, the principal reason for the spouse's employment is the health care benefit. (For example, being a teacher's aid pays fairly little, but you get relatively quite good health care coverage.)
Before Matasano got group coverage in '06, that's how we handled it; Erin took a job in a school system. Erin works with us now, which is a much better state of affairs.
EDIT: s/principle/principal/ #morning fog