Bank runs are bad when there isn't a full reserve. Coinbase says it has 100% reserves.
Bank runs are how fraudulent exchanges are caught: Bitcoin is self-auditing, and either you have it or you don't, there aren't IOUs or paper receipts.
Fractional reserve banking is a prisoner's dilemma, we all marginally benefit from the status quo of credit/debit/interest, but in a crisis, the first people to pull out win, and everyone else loses.
https://coinmarketcap.com/currencies/bitcoin/#markets