I like Inkscape a lot, but there are still cases where it just doesn't work well. The import of postscript or PDF produces some strange results sometimes, especially with text. That is something the commercial alternatives still do quite a bit better.
The speed increase is nice, Inkscape could be painfully slow on complex drawings with lots of paths.
For me the PDF import and export already works well enough: it's been years since I printed a PDF form just to fill it, sign it and then scan it to email it back. I just open the PDF in Inkscape, fill it with the text tool, insert à JPG of my hand signature, save it, and send the resulting PDF back. The administrative efficiency I gained with this technique is gigantic, especially because I don't have to wait to have access to a printer and a scanner to do such things anymore.
When you want to edit the text a bit (so not just to fill forms, but actually edit a PDF/EPS, extract a figure from a paper and rework some text), in 0.48 imported text looked nice initially, but as soon as you start changing a single character the whole text block gets completely wrong (misaligned, writing new characters over the beginning of the text instead of appending...)
The speed increase is nice, Inkscape could be painfully slow on complex drawings with lots of paths.