Even pure water can be harmful. A few years ago a couple guys ended up in coma at a nearby Buddhist temple after a "cleanup weekend" where they were fasting and drinking lots of water (this water OD condition is called hyponatremia). Of course nicotine is more dangerous than water, yet I can't recall a death by overdose of it.
> Of course nicotine is more dangerous than water, yet I can't recall a death by overdose of it.
There actually are some cases if you go looking. Nicotine oil was famously used as a poisoner's tool for a while, prompting some of the early toxicology screens, but these days, most of the cases are accidental. I recall reading about an Israeli case, IIRC, where a child drank some of the e-cig liquid its father hadn't put up high enough.