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The FDA is considering a black label warning for acetaminophen and recently changed the max "recommendation" down from 4 grams daily to 2.3g (IIRC). It is most definitely a liver toxin with therapeutic index that's not so amazing.

People get prescribed ratios of 100:1 APAP:hydrocodone (750/7.5 for example) - it's idiotic from a health and safety perspective. If you need opiate painkillers such as hydrocodone or oxycodone, the extra APAP is unlikely to be of much benefit, and you can always just take some APAP on the side. The APAP is there purely to "prevent" abuse.

I'm not suggesting the "Government is poisoning people" as a conspiracy, I'm suggesting the same idiotic politics and ideas at play during alcohol prohibition are still alive.




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