Self-driving cars will kill air travel for distances shorter than an overnight car trip. Or we will suddenly find that airlines' customers are not a security risk and deserve good service throughout their trip.
Not really though. I regularly travel 1000 - 1500 km on US domestic flights for business on Embraers and CRJs. It's way too long a trip to do by car and high speed passenger rail isn't really a thing that exists here in the US.