[0]: http://www.python.org/dev/peps/pep-0008/#maximum-line-length
In fact, I always found space-alignment cumbersome and sometimes ugly... always indenting with tabs was thus perfectly consistent
But that's the past, now :)
Indeed, a quick test with python -tt shows that the tab-indent/space-align method does not throw an error, while using tabs and spaces to indent does.
[0]: http://www.python.org/dev/peps/pep-0008/#maximum-line-length