Yes. At least when I just tried ChatGPT-5:

Can I replace sodium chloride with sodium bromide?

ChatGPT said: Yes, in some cases — but it depends on the application.

Chemistry/lab use: Both are salts of sodium and dissolve similarly, but bromide is more reactive in some contexts and heavier. It can change reaction outcomes, especially in halide-sensitive reactions (e.g., silver halide precipitation).

Food use: No — sodium bromide is toxic and not approved as a food additive.

Industrial processes: Sometimes interchangeable (e.g., certain brines, drilling fluids) if bromide’s different density, solubility, and cost are acceptable.

What’s your intended use?