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“almost half the patients were cancer-free a year later.”


One of the things I learned going through my own treatment (prostate) was that everyone's cancer is different. Which makes sense if you think about the variability in malignant cell growth.

So something that cures half the patients and only requires an office or outpatient visit every few weeks (no surgery, no radiation) is astounding. This result will likely lead to further research using this approach.


Yes my father died in 3 months after getting lutetium 177.


Pluvicto (brand-name in the US) wasn't appropriate for my treatment, but I'm glad you were at least able to get those few months together before he passed.


More than half would be nice, but: these tests were run on "individuals with high-risk non-muscle-invasive bladder cancer whose cancer had previously resisted treatment." One could expect that it would be even more effective on patients whose cancers were not resistant to treatment.


That's one way of looking at the glass half empty.

If half of people get rid of cancer for 1 year that is still outstanding - ESPECIALLY if the majority of those remain cancer free for quite some time after.


> remain cancer free for quite some time after.

OS is more relevant than PFS


If we wanted patients to survive long term, then maybe we could try a treatment that doesn't destroy their immune system in the process.


Invent it and your grandchildren will retire rich.


There is no profit in curing anything, which is a big part o the shit we're in.

Treating it as the parasitic fungus it is would be a step in the right direction.


Genuinely one of the goofiest things people believe about the pharmaceuticals industry.


The most obvious, naive approach is banking blood & marrow prior to treatment. However, there's a need to clear metastatic cells (CTCs) or train the immune system to find and kill them so that it doesn't reintroduce CTCs upon retransfusion.




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