It happened with someone I know. He tried psychedelics in a weekend at the beach house scenario for the first time as a middle aged man. He liked the experience and then started reading about LSD microdosing, so he decided to try that.
Over the course of a few weeks he began to slide into what was clearly schizophrenic delusions. He became obsessed with what he presumed was a vast conspiracy to murder him and take his money, interpreting ordinary events like someone cutting him off on the highway as being part of this.
Thankfully he's got a good partner and support network, got into therapy, and now is doing fine.
I have a pretty live and let live attitude over psychedelics, but I do hate when aficionados pretend there aren't risks or downsides.
On a less dramatic scale I know people who've tried it and hated it, and that's very much a possible outcome as well. It's crappy when aficionados flip that around into somehow being a square or whatever.
It is quite irresponsible to take a psychedelic drug and then drive a car.
So called microdosing of psychedelics is generally rubbish, the way they're distributed means you have no idea whatsoever what dose you're actually taking and if you want to live with a 5-HT2a tolerance, just go on a trip dose and you're good for a few months.
Edit: And with some of these substances one should expect cardiac toxicity if dosing every day, due to serotonin receptors in the heart.
Over the course of a few weeks he began to slide into what was clearly schizophrenic delusions. He became obsessed with what he presumed was a vast conspiracy to murder him and take his money, interpreting ordinary events like someone cutting him off on the highway as being part of this.
Thankfully he's got a good partner and support network, got into therapy, and now is doing fine.
I have a pretty live and let live attitude over psychedelics, but I do hate when aficionados pretend there aren't risks or downsides.
On a less dramatic scale I know people who've tried it and hated it, and that's very much a possible outcome as well. It's crappy when aficionados flip that around into somehow being a square or whatever.