I use a little `chrome-new` script to develop (and sometimes take video calls or use buggy apps) against a totally clean fresh Chrome profile, then I use Firefox with uBlock Origin and uMatrix for daily driving.
The first line lets me override which Chrome version I launch if I want to try instead google-chrome-stable or google-chrome-beta for example. I keep them all installed from the AUR on Arch.
Better just use 'HOME=$TMPDIR chrome <args... > without the export. With export the Home variable will persist for the current shell, potentially leading to unwanted results.