This job isn't what you thought it would be.
You know there's no future in this job or this company, none that you want anyway.
You have an offer for a better job elsewhere.
Your new boss is adding introducing red tape.
Your new boss is dumber than your old boss.
Your team's best / most experienced people are jumping ship.
you do not feel like helping any team members
you feel tenseness around your heart area whenever something related to work is on your mind
A kind person with a strong passion and always open to speaking her mind.