I like being able to use Node in Jupyter, but I can't say that how I'm using it feels as natural as it does with Python. I'm way stronger at python than node so it was pretty hard to get set up with it.
There's also probably a way to do it, but I haven't figured out how to use ESModule imports in Jupyter, so that's been a bit annoying also. It also hasn't crossed my mind until literally now, that one could write typescript in jupyter notebooks given that typescript needs to be compiled.
Do you have a link to your current work? I think I'd be interested