I think they don't mean it in the literal "you physically can't tell the direction of charge at all" sense.
As you say, the very fact that we know the real direction counters that. They mean that within the abstract context of electronics presented in introductory physics, the real direction of charge doesn't matter and cannot be determined. As long as you pick one consistent convention and stick to it, the math will always work out the same, since depending on convention, all the directions and signs are equally flipped. The real direction of charge only matters when you get deep into the details (eg semiconductors).
At the level of detail of introductory physics, it's effectively a symmetry, similar to how given the simultaneous flipping of charge, parity and time, you cannot tell the difference.
I think there might be a difference. From our experience with air we know that blowing and sucking are not quite the same. Blown air has a much greater capacity for direction than sucked air. I would assume that this is because the when we blow we add additional molecules and we get to decide the inertia of those molecules, but when we suck we take away molecules and they have the inertia they have.
I would suspect that the same goes for electrons.
An electron gun would (as used in old CRT monitors), would be a very striking example of this - I doubt we could make an electron-hole gun (though shooting positive ions could work, but that's not quite the same thing) - but it may be possible to observe in more normal conditions too?
An electron gun produces a beam that contains only electrons; there is no conductor, and I think holes can exist only in the presence of a conductor. So you can't shoot a beam of holes through a vacuum. But if the material between the gun and the screen were a semiconductor, maybe you could draw pictures on the screen using a beam of holes? I mean, I don't see why a beam of holes can't be focused just like a beam of electrons.
> I mean, I don't see why a beam of holes can't be focused just like a beam of electrons.
Wouldn't electrons rush in to fill the holes from every direction, rather than just the intended one? That's what my intuition says anyway. So yeah, my guess would be that it is in fact not possible.
That blade cuts both ways; the electron beam in a CRT travels through a vacuum, there's nothing to "rush in". A hole beam would have to travel through a medium with no free electrons.
As you say, the very fact that we know the real direction counters that. They mean that within the abstract context of electronics presented in introductory physics, the real direction of charge doesn't matter and cannot be determined. As long as you pick one consistent convention and stick to it, the math will always work out the same, since depending on convention, all the directions and signs are equally flipped. The real direction of charge only matters when you get deep into the details (eg semiconductors).
At the level of detail of introductory physics, it's effectively a symmetry, similar to how given the simultaneous flipping of charge, parity and time, you cannot tell the difference.