Which is why you don't go through HR. Every piece of hiring advice from a reputable source will tell you to find out who the person is making the decision and go to them rather than firing a resume to jobs@example.com. As patio11 said, "resumes are an institution created to mean that no one has to read resumes." [1]
I've had experience in the past being referred for a job by someone on the inside, and still getting turned away by HR for undisclosed reasons. In some companies, even if someone wants to hire you specifically, HR still gets in the way.
[1]: http://www.kalzumeus.com/2012/01/23/salary-negotiation/