"In the reviewed studies, there was a high prevalence of Adv36 in all age groups, which exceeded 64% among adults and 73% among children and adolescents with obesity and/or metabolic disorders. The vast majority of the reviewed studies have shown a statistically significant association between Adv36 and obesity, adiposity, and related alterations, whereas only a few studies presented divergent results."
Adenovirus 36 prevalence and association with human obesity: a systematic review
"The obvious reason for obesity is eating too much sugar and refined carbohydrates. But statistically how much does this add to the risk of obesity?
A 2019 meta-analysis of different food intake studies and weight gain showed that consumption of refined grains increased the relative risk of obesity by 5% and the consumption of sugar-sweetened beverages increased the relative risk of obesity by 10%. Eating more legumes, fruit, and fish all tilted the scales in the other direction, reducing the risk of obesity by 5-15%. The study concluded, “The dose-response meta-analytical findings provided very low to low quality of evidence that certain food groups have an impact on different measurements of adiposity risk.”"
Food Groups and Risk of Overweight, Obesity, and Weight Gain: A Systematic Review and Dose-Response Meta-Analysis of Prospective Studies
I was slack and didn't read your links last night, sorry.
From what I can gather, infection with adenovirus-36 basically improves glycemic control... ostensibly a good thing? I couldn't find whether adenovirus-36 was a persistent infection, or whether it only affected patients for a short time, but then they failed to lose weight after the infection had cleared.
This author states that the reason for obesity is eating too much sugar and refined carbohydrates. Why is there a distinction between refined and unrefined carbohydrates? There's no explanation for this, it's treated as given. It's the same chemical makeup, all that changes is the glycemic index. In other words, it's the same poison, it just takes longer to absorb.
The linked study backs this up, but makes no sense from a glycemic load point of view. I notice that vegetables are lumped in one category. Potatoes are not the same as celery. As are fruits, yet blueberries and mangoes have a vastly different sugar content. To add insult to injury, this is a meta-analysis of observational studies, which are notoriously unreliable.
Let me back all this up with a different meta-analysis of interventional trials which treats all carbohydrates the same.
Ketogenic Diet Benefits to Weight Loss, Glycemic Control, and Lipid Profiles in Overweight Patients with Type 2 Diabetes Mellitus: A Meta-Analysis of Randomized Controlled Trails
In my opinion, it's mostly the excess carbohydrates now compared to what we ate 100 years ago. Occam's razor and all that.