I’ve lived here nearly 50 years, and even had a Lake Shore Drive address for a few years. LSD isn’t very common at all in my experience. Cabbies in particular all say “Lakeshore” or “Should I take Lakeshore?”. Same with traffic reports on WBBM etc. Everyone who lived in my building said “<numbers> Lakeshore” when asked where they lived.

The economy of two syllables instead of three wins I guess.