Glad you mentioned this. I'm a avid biker and endurance runner. I'm diagnosed with PVC a few years ago. I went through two rounds of ablation, both failed. Now I take Flecanaide to keep the rhythm but I want seek second opinion now, thanks to this tweet.
Maybe this helps: some anti depressants (like Zoloft) modify neurotransmitters, like serotonin. In my case at least, having a lot of unused serotonin laying around caused arrhythmia. Most doctors have never heard of the side effect (I'm not sure if it's even listed), but in my case stopping / starting Zoloft behaved as reliably as a light switch on my arrhythmia, albeit with cause and effect delayed by a few weeks.
The sad thing is I took Zoloft for years, mostly because my doctor said it's not wise to stop. In my case it was bad advice, as arrhythmia is a self perpetuating condition that gets worse if you let it linger. I use Zoloft to get past a high stress few years in my life (running my own business). Once that was over I should have stopped taking it immediately.
