I wonder if this is an opportunity to detect intelligent life. If the black hole is affecting any intelligent life on the way, they might do something to save themselves or their planet, which might be detectable?
Please note that the black hole is causing star formation from gas, not moving star systems. From what I gathered from the article, there are very few stars actually in its path, and it is mostly just plowing through a large gas cloud.
If they could do something on a scale to stop (or even avoid) a runaway black hole they'd have to be enormously powerful. I would think even for species well beyond our capabilities the only option would be to flee.
By our current understanding the only thing one could do to a black hole is increase its mass (useless) or attempt to change its path gravitationally (requiring a massive amount of gravity -> requiring a massive, massive amount of energy)
Fleeing probably makes the most sense for any species.