East Bay (by which I assume the Tri-Valley and LaMoraga+Walnut Creek) always had a massive tech presence - going from Livermore+Sandia+Berkeley Labs to PacBell to PeopleSoft to HPC@Cheveron+PGE to Workday+Veeva today and the Telcos in LaMoraga+Walnut Creek. Most Asian and White techies with families try to buy houses out there hence why you see Palo Alto level housing prices.
If by East Bay you mean Oakland and its denizens, I don't see it happening. Oakland+Berkeley local govt makes SF appear very startup friendly.
Since SF has some of the worst governance in the country, maybe it won't last that long. There's always East Bay.