In my experience, it doesn't handle "unusual" boot disks well. For example, images not using GRUB / ISOLINUX, or the usual modern windows bootloader. I've had issues with Haiku OS and Redox OS for some examples. I still keep a VenToy disk for most uses, and another one for when VenToy doesn't work
Yes I would sort of expect it to struggle/fail with more unique disc images. I only ever use it with official ISOs for this reason. If I don't see the OS listed on the compatibility list I tend to not waste my time seeing if it works or not.
