Perhaps he will take some time to clear his head. Is there a monastery in South America where he can repent? Preferably one with no extradition treaty?
All the countries in South America have extradition treaties with the United States. If he's looking for a monastery, he should head to a Buddhist monastery in Vietnam.
Taking full responsibility would be liquidating his assets to make all customers as whole as possible, even if it leaves him destitute. Lack of responsibility/consequences for the capitalist class is the root cause for many of the social problems we have today.
It's not OK that we hugely reward taking risks to capital and then largely isolate the "risk"-taker from the consequences of failure when they materialize.