Hacker News new | past | comments | ask | show | jobs | submit login

I'm not sure you can say this that confidently. "Autophagy can suppress or promote tumors depending on the developmental stage and tumor type." - https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6257056/



The point is prevention. It promotes tumors once they already exist. It prevents them before they do.


So you have a clinical study showing cancer prevention on this extreme diet? Over what time span and how many individuals, and across what variety of geographic areas and other life experience?


Most diet tracking nutrition research is not that good, consisting of surveys that ask you what you've eaten for the past year, from memory and then doing correlations. Most people don't remember what they've eaten last week.

I think to do something really accurate nutrition wise would cost way too much money and take too long, so it mostly doesn't get done well.

So unless you do something specific with faith practice communities that are good about their strict diets and fasting, like Buddhist monks, there probably isn't much good research data for that in the first place. And then that has issues with controlling for other things, like meditating a lot, etc.


https://pubmed.ncbi.nlm.nih.gov/33197913/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612215/

Its pretty well know mtor/igf-1 stimulates growth. All growth. This is great for youth. Not so much for aging.

https://m.youtube.com/watch?v=AjSl4n_KdOY


Both of those papers are about the treatment of cancer, not about the avoidance. I don't have the internet connection needed to watch a video, but the video appears to be about longevity.


The only support for this point I've found is in a few studies in mice. Is there other studies I'm missing or are you making recommendations based on a few studies in mice?

"Studies on autophagy-deficient mouse models indicate that the basal levels of autophagy can suppress tumor formation at the initiation of tumor development." - https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6274804/




Consider applying for YC's Spring batch! Applications are open till Feb 11.

Guidelines | FAQ | Lists | API | Security | Legal | Apply to YC | Contact

Search: