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How do they find mice with ALS?



Mice models which have pretty much nothing to do with actual ALS.


You're getting downvoted, but this is exactly right. We create a mutant mouse that has symptoms that are somewhat similar to the disease we're studying. Then we find a drug that cures the "disease" in the mouse. Then we try it in humans and it fails and we make the shocked Pikachu face.


Similar deal with Alzheimer's.


Can you clarify? Like, I would assume that if it's still named "ALS" that there are some commonalities. If those differences are big enough (to the extent that the models are nothing alike) why is the naming shared?

Happy to accept "bad journalism"!


I dunno, but when they do research on MS (multiple sclerosis), they do it on mice with experimental allergic encephalomyelitis (EAE), which is an animal model of MS.


If a medical researcher can't give a mouse cancer and cure it he ain't any good.

Somewhat better ones can do the same for ALS it seems.




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