You would essentially need a Terminator robot to enforce it. Something deployed independently that could destroy you if you deviated from the specified mission, and could not be reasoned with or recalled. This might be possible someday, maybe even soon. Smart contracts, orbital lasers, etc. But then the org would just spend all their time arguing about how to define the mission and protocol and never get it done.
But another reason is that organization would probably just stop being funded when it upheld its hard-coded mission in ways that were unpopular. If the mission is that you must advocate for providing speech/payment platforms for someone who is saying heinous things, people will just stop donating to you. The org has to survive to execute its mission, and it needs to adapt to survive. That will always result in drift, decay, and death.
And the powers that be would not let such an organization gain enough ground that it could become independently wealthy.
But another reason is that organization would probably just stop being funded when it upheld its hard-coded mission in ways that were unpopular. If the mission is that you must advocate for providing speech/payment platforms for someone who is saying heinous things, people will just stop donating to you. The org has to survive to execute its mission, and it needs to adapt to survive. That will always result in drift, decay, and death.
And the powers that be would not let such an organization gain enough ground that it could become independently wealthy.