In theory, sure. However, having done that dance before, the limitations between a degoogled Android (basically open source apps only, since F-Droid doesn't allow proprietary apps, and nearly all proprietary apps depend on Play Services APIs anyways), you end up with something less useful than a PinePhone.

And at the end of the day, Android was written by Google for Google to serve Google. Trying to use a phone as your daily driver running developed by your enemy is hardly a way to get through life. Just get a phone that doesn't hate you. Like a PinePhone. Or an iPhone, which has all sort of issues but at least gives you a reasonably private and secure device at the expense of gobs of money.

MicroG may still ping google services sometimes, but it is not a root level backdoor into my phone. Most proprietary apps I've tried work. Bank app, dating apps, slack, visual voicemail, venmo.