Similar claims were also made by Dr. Lustig’s book Metabolical earlier this year, which of course is more concerned with the diabetic aspects but indeed considers Alzheimer's etc. metabolic disorders.
Not seeing Bredesen on the bibliography so I think the research is independent, some related citations from that bibliography:
G.J. Biessels and F. Despa. “Cognitive Decline and Dementia in Diabetes Mellitus: Mechanisms and Clinical Implications,” Nat. Rev. Endocrinol. 14 (10) (2018): 591. https://www.nature.com/articles/s41574-018-0048-7
B.J. Neth and S. Craft. “Insulin Resistance and Alzheimer’s Disease: Bioenergetic Linkages,” Front. Aging Neurosci. 9 (2017): 345. https://doi.org/10.3389/fnagi.2017.00345
S.S. Dominy et al. “Porphyromonas gingivalis in Alzheimer’s Disease Brains: Evidence for Disease Causation and Treatment with Small-Molecule Inhibitors,” Sci. Adv. 5 (1) (2019): eaau3333. https://www.science.org/doi/10.1126/sciadv.aau3333
M.P. Pase et al. “Sugary Beverage Intake and Preclinical Alzheimer’s Disease in the Community,” Alzheimers Dement. 13 (9) (2017): 955. https://doi.org/10.1016/j.jalz.2017.01.024
V. Berti et al. “Nutrient Patterns and Brain Biomarkers of Alzheimer’s Disease in Cognitively Normal Individuals,” J. Nutr. Health Aging 19 (4) (2015): 413. https://doi.org/10.1007/s12603-014-0534-0
S.M. Raefsky and M.P. Mattson. “Adaptive Responses of Neuronal Mitochondria to Bioenergetic Challenges: Roles in Neuroplasticity and Disease Resistance,” Free Radic. Biol. Med. 102 (2017): 203. https://www.sciencedirect.com/science/article/abs/pii/S08915...
So the claim is that ultraprocessed food is essentially making your mitochondria sick, and the recommended diet adjustment is not very different from
Bredesen’s approach.
Not seeing Bredesen on the bibliography so I think the research is independent, some related citations from that bibliography:
G.J. Biessels and F. Despa. “Cognitive Decline and Dementia in Diabetes Mellitus: Mechanisms and Clinical Implications,” Nat. Rev. Endocrinol. 14 (10) (2018): 591. https://www.nature.com/articles/s41574-018-0048-7
B.J. Neth and S. Craft. “Insulin Resistance and Alzheimer’s Disease: Bioenergetic Linkages,” Front. Aging Neurosci. 9 (2017): 345. https://doi.org/10.3389/fnagi.2017.00345
S.S. Dominy et al. “Porphyromonas gingivalis in Alzheimer’s Disease Brains: Evidence for Disease Causation and Treatment with Small-Molecule Inhibitors,” Sci. Adv. 5 (1) (2019): eaau3333. https://www.science.org/doi/10.1126/sciadv.aau3333
M.P. Pase et al. “Sugary Beverage Intake and Preclinical Alzheimer’s Disease in the Community,” Alzheimers Dement. 13 (9) (2017): 955. https://doi.org/10.1016/j.jalz.2017.01.024
V. Berti et al. “Nutrient Patterns and Brain Biomarkers of Alzheimer’s Disease in Cognitively Normal Individuals,” J. Nutr. Health Aging 19 (4) (2015): 413. https://doi.org/10.1007/s12603-014-0534-0
S.M. Raefsky and M.P. Mattson. “Adaptive Responses of Neuronal Mitochondria to Bioenergetic Challenges: Roles in Neuroplasticity and Disease Resistance,” Free Radic. Biol. Med. 102 (2017): 203. https://www.sciencedirect.com/science/article/abs/pii/S08915...
So the claim is that ultraprocessed food is essentially making your mitochondria sick, and the recommended diet adjustment is not very different from Bredesen’s approach.