My own mom has it right now. It's a godawful disease but her choices are equally godawful and they are getting monotonically worse with her decline. Her brother got it too and died horribly. Her other brother became a health not late in life and did not succumb to dementia but rather died of natural causes around 90 a happy and content soul. So I guess in both instances here we are both anecdotal single data points. But I think we can agree this is a horrible disease.
Absolutely. In the case of one uncle he was tea total, healthy diet, distance running, skiing up to his 70s when he got Alzheimer's. Declined in 2 years to the point where he couldn't be at home as he was too strong for his wife to handle. Covid proved the end of any attempt to cling on to his past as it was made illegal for family to visit him. He's gone completely now. But I suspect his physical fitness will see him last longer than he should.
It didn't help. If anything in my observations it made things worse. Though it's a meaningless sample size.