I mean yes, but there is a rather specific window where they make sense: at ~1-80% of c. Lower speeds it doesn't make sense to engage in interstellar travel at all, because even travelling 100s of years won't get you anywhere. At higher speeds it doesn't make sense because of time dilation.

But that's a... pretty important window. There are not-completely-bonkers hypothetical spacecraft designs that could get to, say, 0.2c. There's nothing particularly plausible that could get to 0.99c.