As always it's a matter of judgement which businesses are ok and which are a nuisance.
Any number of desk job type businesses would not worry me much. Strip joints tend to be open late at night and have lots of traffic, so that's the other end of the spectrum.
AirBnB for me is not necessarily at the desk job end but they're also not at the strip joint end. I think it's up for debate.
The matter of judgement comes down to "Who's judgement?"
AirBnB clearly thinks it is fine. The people on either side of AirBnB renting may think it is fine. People living next door don't get a say, and yet have to deal with the social outcome. They want a say.
Why do they want a say?
Reputation with your neighbours is the outcome of repeated interaction - prisoners dilemma-ish in action.
Humans prove time and again their behaviour can't be guaranteed when they perceive they are anonymous, or the interaction is a once off.
I think "it is up for debate" as to how to proceed in future. I don't think it is up for debate that we can continue without change.
There is a reason zoning exists.