Sure, but it's not as big as an ecosystem. Knowing JavaScript at this point is way more valuable than learning VBA. I'm not saying VBA is bad, I think visual basic is great, I have fond memories of it, but reality is JavaScript is going to be what companies are going to want their employees to know.
Can JavaScript use COM libraries and windows APIs? The JavaScript ecosystem is big but I doubt it covers much of what a typical VBA application needs. I think C# or another .Net language would be more suitable.