I've been working remotely for almost a decade, and never have I experienced, or had coworkers who experience the isolation and troubles that I'm starting to hear about. But I am now realizing that we also don't define ourselves by our work. We do have families, lives, friends, and hobbies. We are quite busy people with full lives, who happen to sit down for a chunk of each day and do our work.

Maybe that is the key - go figure out who you are, build up your life, and only then start working remotely.