Yeah, myelination usually has more pronounced effects on peripheral nerves as they had long wrapped axons. I’m glad your son did not have severe demyelination problem. I don’t want to sound brutal but the mild effect mutation caused could also be the reason he survived the mutation
He probably would not have survived when born a hunderd years ago or in a less developed country, because he relied on tube feeding for several years. To me, you did not sound brutal. A side effect of having better medical intervention techniques, is that the general fitness of human genetic material is getting lower. If you combine this with the higher age at which children are conceived, it might make genetic genering inevitable in the future for the human species to survive.
Yeah, I totally agree your point. The better medical condition inevitably making those mutations deadly years ago now survivable. These conditions are also called rare diseases by NIH. They won’t worth the effort for pharma to develop traditional treatment. But genetic manipulation like crispr might help to cure, it might be late for your son, but might still helps.
