I like how almost all the ports are on the right. You will not want to use a mouse with this machine if you're a righty, there will be at least one cable in the way.
I am rightly, but a few years ago I tried to use the mouse with the left hand. To my surprise it took just couple of days to adjust. Clearly with the right hand I could press buttons faster, but the precision of mouse positioning was just as good.
The previous poster was referring to the cables on the right getting in the way of using a mouse to the right of the unit, not that you couldn't use any the right ports for putting a mouse in