Screen time is very limited in our house, but having it for traveling is absolutely necessary. We have had some very long and very loud flights with my daughter and I am willing to do anything to prevent that again, including setting an iPad in front of her for the entire flight.
Sago Mini is a good bet for preschoolers in general (disclaimer - I was part of starting Sago Mini, but have no connection to them now). You can buy them individually and then I'd probably start with Sago Mini Pet Cafe or Sound Box. There's also Sago Mini World, which is a subscription that has loads and loads of things in one place.
Other good options for this age group is the Peekaboo-series from Night & Day Studios and Petting Zoo from Fox & Sheep.
If you're looking for something more educational, take a look at Khan Academy Kids which starts at around age 2. Fantastic and completely free.
My daughter doesn't quite have the dexterity to assemble duplos yet, she is still in the "knock the tower over" and "destroy everything dad builds" phase. I am very excited to get her some when she's ready for them!
I meant lego duple games on phone or tablet. They are for that age range. One of them is about mama duck searching for 5 baby ducks. Another about rabit going to buy ice cream, yet another us train. Kind of adventure games for toddlers.
There are duple animals waving when you touch them and happy music.