I'm a college dropout who's been in a position where I've had to interview people and make hiring decisions. I always hire based on who I'd most like to work with. Sometimes that candidate has a degree from a very prestigious university, other times they don't, but I always hire the person who I think I'll learn the most from or whom I think will add the most value to the company. Grades and the school you went to never tell me those things, it's your interview and personal projects that tell me that.