Not really. I've applied for a startup, got accepted, the next day received a one in a lifetime opportunity to do something I've been dreaming of (security research at a huge and famous company). Went to do the dream job only to quit after 6 weeks and return to the startup. Best decision ever. I didn't win the lottery ticket, but I am also not coming back to a regular job. Yes, you usually get paid less (or much less), yes my peers climb the corporate ladder, have better cars and houses, but I have a more rewarding job, I get to work remotely and travel often, and I can work from home whenever I want. I also hate the hierarchy that eventually comes as the company grows.