Mark Pilgrim's http://diveintopython.org/ is a good continuation to this book if you're interested in learning Python. It's also free, and there's a more recent version for Python 3 at http://diveintopython3.org/
The grandparent comment links version 0.1 of the book, get the current version (0.5 as of now) from the book's website at http://learnpythonthehardway.org/
(I found that out in the process of attempting to report an error in version 0.1 - it's already fixed in 0.5, and 0.5 is 4x longer.)
Posted this since I've seen so much praise for Zed's Python book here on HN.