Just upgraded to an NVMe for my primary drive... my mb had a x2 nvme slot, but it didn't work... luckily I got a pciex4 adapter, frankly, I know it's a bit faster than the SSD, but in general use, I haven't noticed the difference so much. Aside from node builds are a bit faster (which tends to touch a lot of random files on disk). General use hasn't been noticeable.