Not the grandparent, and slightly offtopic, but I think it is inhumane to raise children with problems that would affect their quality of life. Preferably this should be detected before birth, but if it's not possible but becomes obvious just after birth I would prefer to euthanise my baby than a life in pain.
No, it doesn't, and obviously every situation is different and needs a different analysis. Personally, I would err towards having healthy children that do not require invasive medical procedure to survive at the expense of simply making another child.
Of course this is all theoretical as baby euthanasia is illegal.
I'd be interested to know if your thoughts on this change once you do. I don't think people who haven't had children can really understand how parents feel about their own children. I know I didn't.