Apparently the following (humble and honest) statement made by Doudna to a UC system magazine[1] hurt their case[2]:
>Says Doudna, "Our 2012 paper was a big success, but there was a problem. We weren't sure if CRISPR/Cas9 would work in eukaryotes-plant and animal cells." Unlike bacteria, plant and animal cells have a cell nucleus, and inside, DNA is stored in a tightly wound form, bound in a structure called chromatin.
>Says Doudna, "Our 2012 paper was a big success, but there was a problem. We weren't sure if CRISPR/Cas9 would work in eukaryotes-plant and animal cells." Unlike bacteria, plant and animal cells have a cell nucleus, and inside, DNA is stored in a tightly wound form, bound in a structure called chromatin.
[1] https://berkeley.app.box.com/v/catalyst-9-1 [2] https://twitter.com/antonioregalado/status/83200343447163289...