As the page notes, many Py2 APIs are completely broken with unicode literals, some noisily and others silently (due to implicit ascii encoding/decoding) leading to hard to diagnose regressions in the codebase under Python 2.
I think leveraging PEP414 and carefully using bytes, unicode or "native" literals is a much more resilient mode of operation.
I think leveraging PEP414 and carefully using bytes, unicode or "native" literals is a much more resilient mode of operation.