the EDA tools need your source code (HDL) to simulate or synthesize the design. But with these F1 instances, potentially the model doesn't have that problem. You develop/design an FPGA solution (some type of accelleration), then you provide it as a service. You don't expose your source code to your end customer, or the EDA tool companies.

You do however, potentially expose your source code to Amazon. But possibly not, if you do your design/testing on EDA tools under your control, then deploy FPGA build packages to the F1 instances for hardware testing.