Well I don't know because there isn't really a mine per reactor but I can tell you how much uranium a reactor that size uses. Around 200 tons a year.

As a comparison to coal, 3 million or more tons of coal is required per year for the equivalent amount of power.

Is that 200 tons of ore, or 200 tons of processed uranium?

Rhetorical question. Neither.

A 1 GW reactor needs 200 tons (Mg) of unenriched U3O8 (237.5 kmol). That is typically 0.72% U-235, and needs to be enriched to 3.5-5% (low-enriched uranium) for fission fuel, which is usually UO2.

So the 237.5 kmol of U3O8 contains 5.130 kmol of U-235, which can make 102.6 kmol of UO2 (5% U-235), with a total mass of 27.7 tons. That leaves 609.9 kmol of leftover (depleted) U-238, or 145.2 tons. That typically goes into armor-penetrating bullets and artillery slugs.

That's the downstream side. One ton of U3O8 might mean up to 999 tons of mine tailings--which are less radioactive than the natural rock, as the U-235 has been removed from them. Nevertheless, they may also contain toxic heavy metals that have never before been exposed to weathering.

So let's say up to 199800 tons of tailings that require some additional processing due to potentially toxic runoff. Coal mining also has the same problem with tailings, but coal-mining tailings are often a viscous, corrosive slurry.

200000 tons sounds like a lot of waste, until you compare it to the coal plant.