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Soon it will be a different name under a different symbol.

You cannot break the cycle of hatred with more hatred and violence.


Neurowarfare is the next frontier (*we’ve reached a ceiling in the realm of kinetic weaponry imo).

But the only reliable defense for that is gaining enlightenment, which is both very difficult to scale and somewhat ironic given the context.


The state of the art in cancer treatment currently is personalized immunotherapies spearheaded by companies like BioNTech, etc.

Cancer should be viewed from a system wide perspective in my opinion rather than a location specific disease.

If you really want to get into biohacker territory, figure out how to sequence the tumor’s mutanome distribution and then generate a mRNA vaccine encoding the unique antigen markers of the tumor.

That’s basically what these biotech companies are doing[0]. If you need pointers on where to begin your research, BNT122 is a good place to start.

Good luck. Depending on how much money your friend has, you might be able to make something happen. Consider contacting biotech companies directly.

[0]: https://www.biontech.com/int/en/home/pipeline-and-products/p...


If you’re wondering why you still feel unsatisfied even after having gotten everything you’ve ever wanted and achieved everything you set out to do, consider reading about the story of Siddartha Gautama and his journey of discovery.

The answers you’ve been looking for are there.


This is incredibly sad, Suchir went to my high school and we both went to Berkeley together. He was clearly very intelligent, and I was always sure he'd go on to be very successful / do interesting things.

If you're struggling reading this, I want to say that you're not alone. Even if it doesn't feel like it right now, the world truly wants you to be happy.

The path is open to you:

Old Path White Clouds [0]

Opening the Heart of Compassion [1]

Seeing That Frees [2]

[0] https://z-library.sk/book/1313569/e77753/old-path-white-clou... [1] https://z-library.sk/book/26536611/711f2c/opening-the-heart-... [2] https://z-library.sk/book/3313275/acb03c/seeing-that-frees-m...


If AMD can come back from the brink of bankruptcy, then Intel can too. I believe.

[Edit]: Though it might have to be that Intel literally has to come to the brink of bankruptcy in order for that comeback to happen.


AMD had Lisa Su, who does intel have?


Didn’t they get Jim Keller to design Zen?


Never understood why the government seems to have such a hard-on against Google.

Somehow, Apple / Microsoft / Amazon / … skate by without getting the same beat-down.


In the case of Chrome, I imagine it's because Google has used its control over Chrome to add built in user tracking that reports only to Google, while simultaneously seeking to remove access to the cookies that Google's advertising competitors must have access to in order to compete.

Do anticompetitive things, win anticompetitive prizes.


Probably because the entire world gets its information through Chrome, and since Chrome is becoming increasingly anti adblock, the danger is that billions of people will now be force fed ads.

Besides, plenty of governments had similar hard-ons against MS & IE in the early 2000s, people just have very short memories in the digital age.

> Apple / Microsoft / Amazon / … skate by without getting the same beat-down.

Their time will come. Defending something bad by pointing at others and saying they are also doing it is typically low-effort reactionism.


There are ongoing antitrust lawsuits against Apple, Amazon, and potentially one coming for Microsoft Cloud business.

In any case, this is more whataboutism than anything. The fact that you perceive others as not being targeted doesn't mean that nothing should be done about Google's monopoly on Search.


Hey! Here’s one: ea-2e495d90-801

Invite codes are optional, but you do get an extra 69 points when you refer someone using them :p


We should steer clear of modifying DNA directly until our understanding of biology is much much better.

For now, I think targeting RNA as an intermediate solution is the right approach.


I think there are plenty of diseases where people would be willing to roll the dice on low probability unintended consequences if it meant a massive 100% probability life improvement. This research is great because it reduces our uncertainty about the former option.

That said, I wouldn't wanna be the first person to do elective CRISPR therapy for something that I don't actually need (i.e. LASIK, etc).


Somatic cell modification is relatively safe. Or rather, not existentially dangerous to the species unless both extremely widespread and extremely deleterious.


How are we to learn how biology works better without modifying DNA directly? We learn through experimentation, not sitting upon a pedestal and pontificating for decades.


> Humans don't live for centuries! We can't wait for progress.


Current SOTA (state of the art) treatment for cancer is:

Sequence patient's tumor mutanome distribution, create personalized therapy encoding the top N neoantigens

+

Anti-PDL1 checkpoint inhibitor

+

mRNA encoded albumin-IL2


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